Insilico Cell Mechanics: Finite Element Modelling of cell behaviour in mechanical characterisation
In our group we experimentally analyze the resistance of cells to substrate deformations. In the present project we plan to generate a finite element model of the cell response to biaxial stretching and use it to estimate cell stiffness from the experimental outcomes.
Recording in real-time: development and implementation of real-time 3D tracking algorithms for observation of biological samples.
The spatio-temporal changes of a living organism happen in real time. Observation of these changes is highly challenging even with cutting edge recording techniques. We are aiming to push this limit with our recently developed functional imaging platform.
The role of early trauma on bone structure
In this project, the effects of early trauma on bone structure will be analyzed by microCT.
Molecular understanding of protein misfolding and aggregation in Parkinson’s disease
Each project will focus around biophysical studies of protein amyloid formation as a function of internal and external parameters using the key protein in Parkinson’s disease (alpha-synuclein) as primary target.
Development of smart, antimicrobial implant coatings for open fracture stabilization
This project will combine literature review with experimental work, with the overall goal to develop smart, antimicrobial implant coatings.
Surfaced Enhanced Raman Scattering in Network Metamaterials
The exploitation of metamaterials caused a leap in controlling light at the nanoscale. Here, we will focus on a different class of optical materials, dubbed network metamaterials.The key design principle is a sub-wavelength network with functional connectivity in analogy to other robust networks.
Development of a reflection-type near-field optical microscope
In this project a reflection-type near-field optical microscope will be designed, developed and characterized.
Vorticity Measurements with Steady State Luminescence Anisotropy
While the measurement of velocity is well established in experimental fluid dynamics with various methods, a suitable one for vorticity is an ongoing challenge. The thesis aims to test a new concept for a vorticity measurement.
Exploring the microbial potential for bioelectrochemical production of value-added chemicals from CO2
This project has been evaluated by Formas as “outstanding” with regards to its societal relevance and importance. It deals with some of our societies’ biggest concerns; sustainability in producing our society’s chemicals and fuels from non-oil-based sources, and reduction of our net CO2 emissions.
Enzymatic tools for Seaweed Biorefinery - Biomass deconstruction and extraction of fine chemicals
New enzymatic tools and processes need to be developed for the proper utilization and processing of seaweed polysaccharides as renewable resource. We have different approaches to achieving this, and hence the project can be tailored to the candidate’s skills and interests.
Analysis of leg muscle activity during undisturbed and disturbed walking
A device called the ETH Knee Perturbator has been developed at the RELab. It can induce knee joint perturbations during walking. Measurements of muscle activity while wearing the device and during perturbations offers useful insight in muscle recruitment when gait is disturbed.
Maintaining balance after trips: role of movement patterns
Humans use stereotypical movement patterns to recover from trips during walking, but how we choose which pattern to use is poorly understood. The goal of this project is to determine whether single or multiple responses are necessary to ensure balance recovery after trips in a model of human gait.
Liquid armor? A study of projectile resistance in shear thickening materials
Body armor is used by police and military personnel for protection against gunshots and projectiles. This body armor needs to be both flexible, so that they can move easily and hard, in order to stop on impact and protect the wearer. A shear thickening material allows for both us these traits
How can propionibacterium acnes cause back pain?
The aim of this project is to identify molecular mechanisms that may be explain pain development upon bacterial infection of the intervertebral disc, specifically by propionibacterium acnes.
Engineering the Diabetic Tendon Microenvironment
This project aims to engineer a synthetic hydrogel-based cell niche that mimics key aspects of the diabetic tendon extracellular matrix. Patient-derived tendon fibroblasts will be used to construct a more physiologically relevant three-dimensional (3D) model.
The role of tendon matrix composition in regulating tenocytes fate: A tissue engineering approach.
The goal of this project is to create a 3D in vitro model to study tendon cell-ECM interaction using collagen gels and primary rat tenocytes.
Tendon-on-a-Chip: Developing and characterizing a multi-channels microfluidic device for studying tendon biology
This goal of this project is to refine and characterize a novel approach in designing microfluidic networks that allow to host tendon-like micro-tissue structures for long-term culturing experiments under mechanical stimulation.
Master's project and thesis work opportunity on electrochemical energy storgae (battery) research
Area: Interdisciplinary research at the intersection of chemistry, materials science and electrochemistry with focus on materials development and their electrochemical evaluation for the advancement of safe, inexpensive, and high energy density aqueous and nonaqueous rechargeable batteries.
Flowability improvement of fine powder using atmospheric pressure plasma
Low temperature plasmas are a versatile tool for non-equilibrium chemistry. In this work, we try to generate nanoparticles using atmospheric pressure plasma to enhance powder flowability. The goal is to find a way to change the industrial batch process to a continuous process.
Changes in the expression of mechanosensors with age and degeneration
This project will investigate whether and how the expression of a specific group of mechanosensors – the TRP Channels – changes with age and degeneration in the human intervertebral disc. Methods used in this project will include qPCR, immunohistochemistry and immunoblotting to investigate expressio

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